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Baicalin (BI) is an active metabolite of Scutellaria baicalensis Georgi that prevents excessive apoptosis and promotes repair of mucosal cells by inhibiting PI3K/Akt signaling, elevating the level of Bcl-2 and inhibiting inflammatory response and apoptosis in HT-29 cells (Wang et al., 2022a)

Disruption of ATP-binding cassette B8 in mice leads to cardiomyopathy through a decrease in mitochondrial iron export

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162 Histone acetyltransferase activity of CBP (KAT3A) is required for neurogenesis and memory consolidation in rodents

By contrast, GMP-grade FBS undergoes extensive testing for sterility, endotoxins and viral contaminant, whereas unavoidable batch-to-batch variability can still affect reproducibility, thereby increase overall production costs (van der Valk et al., 2018)