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is the recipient of a Health Research Council of New Zealand Sir Charles Hercus Health Research Fellowship

When tinnitus is worse at night, it may be due to surroundings being quieter and less able to mask the tinnitus sound

Therefore, FSP1 is considered another major ferroptosis regulatory molecule besides GPX4, playing a crucial role in inhibiting ferroptosis

Biochemically, ferroptosis stems from accumulation of lipid reactive oxygen species (ROS) which exceed cellular antioxidant capacity supported by glutathione (GSH), and from inhibition of glutathione-dependent enzymes, such as glutathione peroxidase GPX4 [8, 9]

Thus, it is possible that in young animals, but less so in mature and old, an increase in protein synthesis occurs after exposure to high doses of EtOH, at the expense of GSH synthesis
