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A double-blind, placebo-controlled trial in 90 HIV-positive patients with symptomatic distal symmetrical polyneuropathy found no benefit of intramuscular injection with 1 g/day of ALCAR for two weeks in the intention-to-treat analysis, but there was some pain relief in the group of 66 patients who completed the trial (84)

For example, liposomal systems originally designed for liver targeting can be modified to redirect activity toward the lungs, often with improved therapeutic outcomes

However, it is important to recognize that these findings may not fully translate to human outcomes

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Lewiska A, et al

Behind the link between copper and angiogenesis: established mechanisms and an overview on the role of vascular copper transport systems