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m and the levels of oxidant species were evaluated using JC-1 and carboxy-H2DCFDA, respectively, while redox state was measured by the FAD/NAD(P)H autofluorescence ratio

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Similarly, elevated global DNA methylation, Dnmt activity, and 5-methylcytosine but decreased Tet activity and 5-hydroxymethylcytosine were observed in the GSH-deficient hepatocytes and the liver of HFD-fed mice

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