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The brain produces and responds to many neurotransmitters that trigger or inhibit specific reactions in the body

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Conclusion Our findings demonstrate that all three GLP-1 analogs, semaglutide, tirzepatide, and retatrutide, exhibit significant anti-obesity effects in MC4R KO mice

(2) Lip-1 significantly attenuates renal collagen protein deposition and expression of fibrotic factors in a unilateral ureteral occlusion (UUO) mouse model, thereby alleviating renal fibrosis