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J Clin Endocrinol Metab 76:309317 Beshyah SA, Kyd P, Thomas E, Fairney A, Johnston DG (1995) The effects of prolonged growth hormone replacement on bone metabolism and bone mineral density in hypopituitary adults

Side effect comparison: Nausea: Similar rates between the two compounds Vomiting: Cagrilintide significantly lower (OR 0.38) Diarrhea: Comparable rates Constipation: Similar Injection site reactions: Cagrilintide substantially higher Discontinuation due to AEs: Cagrilintide much lower (1% vs approximately 5-7%) The takeaway: if vomiting was your main problem on semaglutide, cagrilintide may be worth exploring

[Google Scholar] 35.Penick SB, Hinkle LE Jr

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Second, AOD-9604 inhibits fatty acid synthase and acetyl-CoA carboxylase, the rate-limiting enzymes in de novo lipogenesis