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Similarly, topiramate decreased its MDA levels and increased GSH levels in a study on the prevention of flap necrosis after plastic and reconstructive surgery ( However, in a study on the potential toxic effects of topiramate on the liver and kidney of male mice, topiramate significantly decreased the activities of the antioxidant enzymes SOD and CAT, while increasing MDA and NO levels ( In vitro study found that topiramate increased MDA, NO and ROS production in astrocytes, showing a dose-dependent negative effect (Pavone and Cardile, 2003)

As well as the initial attempt to dive onto the animal, the man stays in the water and then swims toward it again in a second attempt to touch it

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[32] however, these variations are not required for the condition to occur and sometimes occur in individuals without narcolepsy

Co-targeting menin and RAS in KMT2A-r/NPM1c AML with activated RTK signaling

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