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Thymosin Beta 4 and a Synthetic Peptide Containing Its Actin-Binding Domain Promote Dermal Wound Repair in db/db Diabetic Mice and in Aged Mice, Philp D, Badamchian M, Scheremeta B, Nguyen M, Goldstein AL, Kleinman HK, Wound Repair and Regeneration, 2003 JanFeb;11(1):1924

J Neurosci 20, 13931403 (2000)

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The results of pooled analysis of pivotal, global studies of roxadustat in the NDD-CKD and the DD-CKD populations revealed that the incidence of vascular access thrombosis and deep vein thrombosis in patients treated with roxadustat was higher than that in the control group ( Kidney disease progression Given the effects of pharmacologic HIF activation in models of CKD appear to be context-dependent and less consistent, the concern that anemia therapy with roxadustat may worsen CKD in certain subgroups of patients was raised

The cumulative effect may contribute to better skin, improved texture, and overall enhancement of skin quality

other macrophage-related markers: (C) TNF and (D) IL-6