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Both compounds have become widely recognised within scientific and research communities due to their unique biological characteristics and the growing body of literature surrounding their mechanisms of action

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After entering the RBC, glucose is immediately converted to glucose-6-phosphate by hexokinase (HK) and then fueled into the glycolytic pathway or into the PPP [182]

The increase in cAMP levels triggers a series of events, including the activation of protein kinase A (PKA)

These findings highlight the potential of polyphenols as GSK3 inhibitors, offering a promising therapeutic strategy to modulate tau pathology and mitigate AD progression (Figure 5ah)

In recent years, NIBS has gained much attention as a promising non-invasive and non-pharmacological approach to fatigue treatment