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Moreover, neutralizing HMGB1 with specific antibodies or depleting HMGB1 reduces inflammatory activation in macrophages, implying that HMGB1 inhibition may be a possible therapeutic strategy for controlling macrophage-mediated inflammation (103)

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In addition, it appears that NAD+ protects muscles from metabolic and structural degeneration [13]

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Digital interventions are required for a close monitoring to help facilitate the achievement of the World Health Organizations (WHO) decade of healthy aging, which is expected to span through 20202030 and focus on maintaining functional abilities during aging [44]

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