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The study has shown that hawthorn POS significantly reduce body weight gain and serum levels of TG, TC, FFA, and LDL-C, while suppressing the expression of inflammatory cytokines TNF- and IL-6 and the macrophage marker CD68 in white adipose tissue

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Unsaturated VPA metabolites (4-en-VPA and 2, 4-dien-VPA) are potent inducers of microvesicular steatosis in rats, whereas VPA itself failed to induce discernible liver lesions at near lethal doses [60]

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