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IGF-1-infused animals show lower vascular superoxide levels and higher levels of vascular eNOS and NO [64]
The nanodrugs were administered intravenously when the tumor volume reached approximately 50 mm 3
Proline dehydrogenase is a positive regulator of cell death in different kingdoms

The objective is to select a concentration that triggers the primary molecular events leading to toxicity, without surpassing a threshold that produces metabolomic signals linked to overall cytotoxicity and significant cell death

The detection limit of the qPCR assay was set to 100 genes/L, which corresponds to approximately 16,000 genes/mL of sample
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