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Description
The p62/SQSTM1 (sequestosome 1) protein, which acts as a cargo receptor for autophagic degradation of ubiquitinated proteins, is up-regulated by various stressors

Pandey et al

& Foley, J

33813386, Mar

Abstract Background Fat accumulation in the liver contributes to the development of non-alcoholic fatty liver disease (NAFLD)

154,156 It also regulates cellular lipid metabolism by directly phosphorylating acetyl-CoA carboxylase (ACC)1 and ACC2, thereby inhibiting fatty acid synthesis and promoting FAO
