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Recent single-cell RNA sequencing (scRNA-seq) studies (287, 288) have further revealed that in CKD, PT cells downregulate SLC7A11 and GPX4 expression, while interstitial fibroblasts upregulate pro-ferroptotic genes (e.g., ACSL4 and LOX), suggesting cell type-specific ferroptosis programs that drive fibrosis

6c, Fig
Liproxstatin-1 has shown potential in preclinical models of lung injury by reducing oxidative damage, inflammation, and vascular permeability (103)

10.1016/j.vph.2018.02.010 [DOI] [PubMed] [Google Scholar] Wang, X.Y

Occurrence of neoplasms in individuals with congenital, severe GH deficiency from the Itabaianinha kindred

BPC 157 protocols vary based on injury type, route of administration, formulation, and treatment goal
