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Description

In patients with insulin resistance which is extremely prevalent in the South Florida population given dietary patterns and sedentary lifestyle factors this means glucose is diverted to muscle tissue for energy use rather than converted to triglycerides for fat storage

These compounds are strictly intended for research use only (RUO) and are not approved for human medical or therapeutic use

A previous study identified genes necessary for MAP survival in dairy calves and permitted us to select a gene to knockout that is essential for MAP survival in vivo (MAP1643, IcL ) or one which is required for intracellular growth (MAP1531c, BacA ) ( Mouse and calf infection trials were employed to evaluate the immunogenicity of two vaccine candidates, confirm the attenuation in calf, and assess the species-specific essentiality of candidate genes