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For example, the genes encoding transferrin receptor (TFRC), glucose transporters and the master antioxidant regulator NRF2 are closely associated with the pathological progression of AD (49)

To expand the therapeutic potential of this approach for neurodegenerative diseases, Fujita et al

Hussain et al., 2019b

J.SzwedaL

DSF/Cu induces ROS generation to trigger nuclear and mitochondrial DNA damage and cytoplasmic release of dsDNA

Timosaponin AIII (Tim-AIII), A steroid saponin, can bind to the heat shock protein 90 (HSP90), which further promotes the ubiquitination of GPX4 and thereby degrades GPX4 [279]
