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It brings youthful appearance by improving skin texture, tone, and hydration

identified a highly conserved N-glycosylaton site in the Ea domain, which regulated intracellular pro-IGF-1Ea level via prevention of proteasome-mediated degradation and subcellular localization [95]

Total testosterone, fasting insulin, and LH levels decreased while estradiol increased after three months of follow-up

Circulation 136, 894903

In the last few years, various GSH modulation-enhanced combinational therapy strategies have been extensively exploited, accompanied by the development of versatile metal-based nanosystems with different structures, functionalities, and treatment performances ( In view of the rapid development of GSH-responsive and -exhausting metal nanomedicines in potentiating cancer therapy, we summarize and outline the recent advancements, mechanisms, prospects, and challenges in this field from different strategies (Scheme 1)

CoAS-SG, glutathionylated CoA