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This system, independent of lipid peroxide and apoptotic-mitochondrial defect, reveals the complexity of GSH-depletion-induced cell death pathways

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Lopez et al., 1996

Conditioned medium was harvested, filtered through 0.45-m filters, concentrated by ultracentrifugation (81550 g, 2 h at 4 C) and stored at 80 C

224 The inefficacy of CAR-T cell therapy can be attributed to multiple factors, among which T cell senescence and exhaustion play pivotal inhibitory roles