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Mechanistic investigation revealed ChaC1/AUR-driven cytotoxicity was attenuated by disulfide reducing agents (e.g., NAC and TCEP), while maintaining resistance to canonical programmed death pathway inhibitors targeting apoptosis, necroptosis, and ferroptosis

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The global contamination of 15% of agricultural soils with toxic metal (loid) species (TMS) including arsenic, cadmium, mercury, and nickel compromises food...
