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reported increased levels of HSPB11 and HSP60 in the tear film of DED patients after acute exposure to dry conditions, a trend that was consistently noted (104)

Third, H 2 O 2 is converted in a spontaneous reaction catalyzed by Fe 2+ (Fenton reaction) to the highly reactive OH

Saeedi, B

Reduced hepatic GSH levels were reported in numerous diet-induced MASLD/MASH rat and mice models (Dai et al

The PPP has been demonstrated to be a major regulator for cellular reduction-oxidation (redox) homeostasis and biosynthesis

CBS and CSE have been reported to re-localise to mitochondria in response to hypoxia, a common feature of the tumour microenvironment, resulting in targeted H 2 S delivery that can stimulate ATP production and protect mitochondria from oxidative stress