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The algorithm first partitions the overall data variance (X) into individual variances induced by each factor (A and B), as well as by the interactions (AB)
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Elevated methylation in this region reduces CTLA-4 expression, causing dysfunctional Tregs to be unable to activate immune regulatory pathways
Heavy metal toxicity can lower energy levels and damage the functioning of the brain, lungs, kidney, and liver [10]

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