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2, 3, 4 Thus, increased ROS production, reduced nitric oxide (NO) levels and reduced antioxidant bioavailability were demonstrated in experimental and human hypertension

doi: 10.1016/j.ajo.2008.12.010

Zhang M, Zou XT, Li H, Dong XY, Zhao W, et al

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13,15 These age-related brain changes manifest in the diminished mental abilities and thinking skills typically associated with old age, namely reduced short-term and episodic memory, difficulty recalling words, slower reaction times, and possibly depressed mood

(3) Several global DILI registries are operational to better define the epidemiology of various drugs, including herbal and dietary supplements