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Interestingly, there is a remarkable absence of cAMP-responsive elements (CRE) and Ca 2+ responsive elements (CaRE) in the promoter region of POMC despite the demonstrated importance of cAMP and Ca 2+ in the intracellular signaling of corticotrophs and melanotrophs

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Kit Components Additional Materials Required Microplate reader capable of measuring absorbance at 405 nm Precision pipettes to deliver 2 L to 1 mL volumes Multi-channel pipettes to deliver 20 L to 200 L volumes Tubes to prepare sample dilutions Ultrapure water 50 mL conical tubes Protocatechuic acid (HClO 4 ) (PCA) Potassium hydroxide (KOH) Assay Procedure Summary Add 50 L of the diluted GSSG Standards or unknown samples to the 96-well microtiter plate

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We excluded studies whose data were not reliable for extraction and analysis, studies reported as abstracts only or thesis, studies whose complete full texts were not available, and studies not published in the English language