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When B12 levels become too low, people may experience symptoms such as: Fatigue or low energy Memory or concentration problems Numbness or tingling in the hands and feet If B12 deficiency becomes severe and lasts a long time, it can lead to nerve damage

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One approach involves capping the peptide ends with N-acetylation or C-amidation, which prevents exopeptidase degradation and enhances plasma stability
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