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Description
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5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that methylates nicotinamide using S-adenosyl methionine (SAM)
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NNMT is abundantly expressed in liver and adipose tissue and pathological conditions characterized by increased metabolic demand, such as some cancers, fatty liver disease, and diabetes
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