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10.1186/s13020-021-00469-4 23 DangY.XuJ.YangY.LiC.ZhangQ.ZhouW.et al (2020)

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Fibrous cap and shoulder regions: smooth muscle resilience versus vulnerability The degree to which plaque stability is influenced by the strength of the fibrous cap is dependent upon the ability of vascular smooth muscle cells (VSMC) to synthesize an extracellular matrix (ECM) and organize the ECM in order to maintain the caps integrity ( Staging is important in this case because vascular smooth muscle cells may be somewhat protected from ferroptosis in early stages of lesion development

Esterline RL, Ji S

Cholinergic signaling can also control peripheral cytokine production by cholinergic anti-inflammatory pathway activity 11