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Beta-3 Adrenergic Receptor (3-AR) Pathway Activation The primary documented mechanism of AOD-9604 in laboratory research models is activation of the beta-3 adrenergic receptor (3-AR), a G-protein-coupled receptor expressed predominantly in adipose tissue

Insulin and beta-adrenergic receptors mediate lipolytic and anti-lipolytic signalling that is not altered by type 2 diabetes in human adipocytes

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Viechtbauer, 2010), employing a random-effect model via the metafor R package (Del, 2015)

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