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[DOI] [PMC free article] [PubMed] [Google Scholar] 144.de Paula S, Vitola AS, Greggio S, de Paula D, Mello PB, Lubianca JM, Xavier LL, Fiori HH, Dacosta JC

In addition, it has circulation-enhancing effects and positive effects on the immune system , which improves regeneration

In I/R + M group, meldonium restores hepatic antioxidative defence mostly through reverse changes relative to those induced by I/R, i.e., through the CuZnSOD and MnSOD activity increases by 50%, the GSH-Px activity and GSH content increase 2.5-fold, and the GST activity decreases by 10% (Table 3)

MACE major adverse cardiac event

Clinical practice guidelines on the evidence-based use of integrative therapies during and after breast cancer treatment

doi: 10.1038/s41598-018-26423-3 152 SwansonKSGibsonGRHutkinsRReimerRAReidGVerbekeKet al