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Gut microbiota-dependent trimethylamine-N-oxide and serum biomarkers in patients with T2DM and advanced CKD

Mounjaro is administered as a once-weekly subcutaneous injection and is typically prescribed when other diabetes medications have not achieved adequate blood glucose control

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(28152637) IV L-arginine might be a reasonable consideration in the following situations: i) Moderate to severe hyperammonemia, without immediate access to hemodialysis ii) Persistent hyperammonemia, despite hemodialysis iii) Hyperammonemia which poses an immediate threat to life (e.g., moderate to severe hyperammonemia with evidence of cerebral edema) A reasonable dose may be: (22642880) Loading bolus of 250 mg/kg (1.2 mM/kg) over 2 hours

Acknowledgments This review article was funded by Lonza Inc