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Staying well-hydrated and resting for a short period post-injection can help alleviate these feelings

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Rais, R., et al

As proteostasis capacity becomes constrained, newly synthesized polypeptides requiring high chaperone support for proper folding may become increasingly vulnerable, rendering neuronal cells more susceptible to damage

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Second, a break is a natural checkpoint: it lets a researcher assess where things stand off-compound before deciding whether to re-run