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6 Within one year of a patients initial episode, those with HZO have a risk of stroke 4.3 times higher than that of all HZ patients (whose risk is 1.3 times that of controls)

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In cultured human aortic endothelial cells, ebselen attenuated hydrogen peroxide-mediated upregulation of pro-inflammatory pathways that are associated with atherogenesis, such as the activation of NFkB and JNK signaling and the increased expression of TNF- and NOX2 [81]

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