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Dietary adjustments may also be necessary in order to incorporate more foods high in vitamin B12

Of these, the majority were conducted in HIC, while only three studies originated from UMIC, and none were identified from low- or lower-middle-income countries

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Single-cell analysis of murine fibroblasts identifies neonatal to adult switching that regulates cardiomyocyte maturation

Other ALDH2 approaches: Many investigational drugs showed promise in pre-clinical studies, including selective and reversible ALDH2 inhibitors (e.g., ANS-6637) and genetic targeting of liver ALDH2 messenger RNA to locally reduce hepatic ALDH2 expression (305, 306)