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doi:10.1016/j.immuni.2020.08.012 10

doi: 10.1126/scisignal.aba3176

Additionally, mRNA expression of iron response element binding protein 2, encodes a master regulator of iron metabolism), and CS (citrate synthase, regulating the mitochondrial fatty acid metabolism) was upregulated in both models, while ACSF2 ((acyl-CoA synthetase family member 2, regulating the mitochondrial fatty acid metabolism) was upregulated only in APPswe/PS1dE9 mice
41,44,50 A single case report noted no recurrence in a 2-year follow-up after discontinuing the treatment

SOD catalyzes the dismutation of superoxide into oxygen and hydrogen peroxide, which is then decomposed into water and oxygen by catalase and glutathione peroxidase [41]

Notes For example, loss and change, freedom of choice versus loss of control, the dignity of the self, a sense of fundamental aloneness, altered quality of relationships, searching for meaning, mystery of what seems unknowable, and death anxiety
