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This opens up the possibility of our gene therapy targeting the GSH system
Glutathione helps neutralize that damage before it builds up
R01-HL079955
The transgenic plants exhibited enhanced tolerance against oxidative stress and increased transcription of antioxidant genes including a GST (Shi et al., 2014)
Y., Chiang, H
62 Thus, consistent with the very low levels of LPO, 55,62 lysosomal ferrous iron translocated into mitochondria promotes MPTP opening and APAP-induced cell death through facilitation of protein nitration, rather than generation of LPO under normal conditions
