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Rutin completely blocked the HFD-induced increase in the ratio of sequestered bacteria/bacteroidetes, and the gut microbiota of rutin-treated mice presented a variable increase in the abundance of the genera Roseburia, Bacteroides, Alistipes, Parasutterella , and Akkermansia and a decrease in the abundance of Lachnospiraceae, Ruminococcus , Erysipelotrichaceae , Faecalibaculum, Proteobacteria and Anaerotruncu