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Metabolism 23 (5), 522532
For example, Liu et al
high betaine levels may lead to abnormal methylation of profibrotic genes (such as TGF- and COL1A1), promoting renal interstitial fibrosis (168)
HPCAL1, rather than SQSTM1/p62 (sequestosome 1), is a specific autophagy receptor involved in CDH2 (cadherin 2) degradation for ferroptosis in cancer cells [151]
Pathologically activated astrocytes exhibit disrupted intracellular signaling or metabolic homeostasis, impairing EAAT2 transcription, translation, or trafficking
From supporting addiction recovery to combating the effects of aging, the therapeutic applications of NAD+ are vast and promising
