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Last reviewed: May 16, 2026 Last updated: May 16, 2026 Written by: Jay Hastings , CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

To thoroughly assess genotoxicity, it is essential to evaluate three primary endpoints: gene mutation, structural chromosomal aberration, and numerical chromosomal aberration, as each of these events is associated with carcinogenesis and heritable diseases

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It has no approval from regulatory agencies such as the FDA for human use and remains in the preclinical research phase

human evidence does not exist, so these are hypotheses rather than expected outcomes