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doi: 10.1016/j.cell.2012.03.042 22 Mahoney-SnchezLBouchaouiHAytonSDevosDDuceJADevedjianJ-C

Correspondingly, MAPK has four classical signal pathways, among which, ERK pathway is the most classical MAPK signal pathway, critical in DKD development

They demonstrate good tolerability in patients with advanced solid tumors, but their efficacy and durability of inhibition require further validation (Carneiro et al., 2025

Chauhan, D

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Sepesi B, Ye Y, Mitchell KG, Zhang L, Gu J, Ji L, Antonoff MB , Hofstetter WL, Rice DC, Mehran RJ, Walsh GL, Vaporciyan AA, Swisher SG, Roth JA, Wu X
