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Epub 2012 Jun 12

Experimental studies have shown that inhibition of miR-34a in mice fed an HFD increases PPAR expression and AMPK activation, which promotes fatty acid -oxidation and reduces TG accumulation in the liver [300]

2015;43(W1):W174W181

doi: 10.1002/gps.2758 59

Chemoprevention of smoke-induced alopecia in mice by oral administration of L-cystine and vitamin B6

Severe cases of homocystinuria are typically caused by autosomal recessive genetic defects and exhibit characteristic clinical features including ocular lens dislocation, marfanoid features and other skeletal abnormalities including osteoporosis, intellectual disability, and thromboembolic disease, the latter frequently being the cause of premature death in affected individuals (28)