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5 Conclusions The present study integrated physiological and transcriptomic analyses to elucidate the influence of Se treatment and Epichlo endophyte infection on glutathione metabolism in F

Clinical and Metabolic Response to Selenium Supplementation in Pregnant Women at Risk for Intrauterine Growth Restriction: Randomized, Double-Blind, Placebo-Controlled Trial

Strober BE, Menon K (2005) Folate supplementation during methotrexate therapy for patients with psoriasis

Potential role of peptidylarginine deiminase enzymes and protein citrullination in cancer pathogenesis

Additionally, inhibition of PKC was shown to reduce NRF2 phosphorylation and transcriptional activity, along with the expression and activity of NRF2-regulated antioxidant proteins [43]

Compounds such as sulforaphane and bardoxolone function as Nrf2 activators, enhancing antioxidant capacity and increasing GPX4 activity, which leads to reduced lipid peroxidation and prevents ferroptosis (71,72)