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Description
Glutathione is a major antioxidant that enhances the effects of other antioxidants, including vitamins C and E, alpha lipoic acid, and CoQ10

J Am Coll Cardiol 68:12471248
reported significant motor improvement assessed by state UPDRS III and axial items of UPDRS following the LCIG addition to DBS, comparable to the control group that switched from oral medications to LCIG monotherapy

To maximize the efficacy of L-glutathione, it is often beneficial to pair it with specific antioxidant co-factors

Redox Regulation via Glutaredoxin-1 and Protein S-Glutathionylation

Furthermore, 4-HNE induces mitochondrial dysfunction by binding to mitochondrial proteins, leading to electron leakage and increased ROS production
