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Description
Acetyl-L-carnitine is a highly bioavailable form of L-carnitine and is able to effectively cross the blood-brain barrier

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In conclusion, colistin targets the mitochondria and induces permeability transition thereof

The authors of this Perspective summarize the knowledge on irAEs that has been obtained from different sources of big data.

ROS and Ca2+ regulate the activity of the mitochondrial permeability transition pore (mPTP)
