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Febuxostat ( Uloric ) may be considered for some patients who cannot take allopurinol, but it carries a higher risk of heart-related death
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Origins as a Mitochondrial-Derived Peptide MOTS-C peptide was first characterized in 2015 by Lee and colleagues, who showed that stressed muscle cells release this peptide, which then translocates to the nucleus to upregulate genes involved in adaptive stress resistance