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ISBN: 978-3-319-29147-5

surgery should be made on a case-by-case basis. In patients already on a prostaglandin analogue, side effect profile and desired IOP reduction play a major role in deciding whether to switch to latanoprostene bunod or the fixed combination

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In the Ras pathway, Erk1/2 as two mitogen-activated protein kinases to transmit mitotic signals, and the HGF/c-Met signaling pathway phosphorylates and activates Erk1/2 after PHx (Spector et al., 1997
