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Backed by Research and Clinical Observations At Kinnection Clinic, research highlights the effectiveness of IV glutathione therapy in rapidly increasing intracellular glutathione levels and reducing oxidative stress

Indications: Overactive bladder Common symptoms include urgency, urinary incontinence, and increased urinary frequency Side Effects: dry mouth constipation QT prolongation urinary tract infection worsening of myasthenia gravis aggravation of decreased GI motility in patients with autonomic neuropathy WARNINGS: angioedema of the face, lips tongue and/or larynx has been reported CNS Effects: agitation, confusion, hallucinations, abnormal behavior & memory impairment in patients taking 5 mg oxybutynin for more than 3 years compared to no use (Thomas & Walters, 2021): increased risk of dementia (adjusted hazard ratio 1.54) increased risk for Alzheimers disease (adjusted HR 1.63) Pharmacokinetics: taken orally by tablet, 5 or 10 mg once daily metabolized by CYP3A4 half life 13 hrs Notes: the estimated Walmart cost for generic oxybutynin is ~$9 for a supply of 30 generic tablets (GoodRx.com

doi: 10.1111/age.13022 123 GdiaMCastellARoccoMCabreraBRodrguez-GilJEBalaschSet al

We required an enrichment score threshold of at least 1 and at least 10 transcripts per cluster for inclusion in the plot in Figure 4A

Drug Interactions MOUNJARO delays gastric emptying and has the potential to impact the absorption of concomitantly administered oral medications