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Description
It also impairs the function of LC by suppressing the expression of steroidogenic enzymes such as steroidogenic acute regulatory protein (StAR), cholesterol side-chain cleavage enzyme (P450scc), and 3-hydroxysteroid dehydrogenase (3-HSD), ultimately reducing testosterone synthesis (111)
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10.1124/jpet.119.258152 97 WangS.WangB.ShiY.MllerT.StegmeyerR
Mls006010946 119
This metabolic complication limits the usefulness of growth hormone for obesity research, especially in populations already at risk for diabetes
PMID 9675162
