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It also induces the expression of suppressor of cytokine signaling-3, which is a negative regulator of leptin signaling [13]

2022 Sep 15;59(9):683-687

Meanwhile, even though your Folic Acid status is great and red blood cells appear normal, not having enough B12 will cause homocysteine to build up, leading to neurological damage and changes in DNA function without you realizing it until symptoms set in

Vitamin B12 deficiency that is allowed to progress for longer than 3 months may produce permanent degenerative lesions of the spinal cord

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