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Similarly, many forms of secondary carnitine deficiency, including some drug-induced disorders, arise from impaired renal tubular reabsorption

Clin Pharmacol Ther 1987

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The leucine structure contains an alpha-amino group, an alpha-carboxylic acid group and a side chain isobutyl group, making it a branched-chain amino acid

Increased cardiac ROS levels have been implicated in HF, but the role of ROS in the pathogenesis of HF was questioned as a result of disappointing outcomes of antioxidant interventions in human studies

697702, doi:10.1177/0269881113515062