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In their study, Mundy et al

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Initiate the dosing regimen for each patient individually, taking into account the patients underlying cause and severity of pain, prior analgesic treatment and response, and risk factors for addiction, abuse, and misuse [see WARNINGS]

doi:10.1139/Y10-001 Distler MG, Plant LD, Sokoloff G, Hawk AJ, Aneas I, Wuenschell GE, Termini J, Meredith SC, Nobrega MA, Palmer AA (2012) Glyoxalase 1 increases anxiety by reducing GABAA receptor agonist methylglyoxal

With the establishment of a diagnostic model for MASLD, the next step is to predict the long-term cardiovascular event risk of this patient

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