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Take 4 ml (approximately 3/4 tsp) orally on an empty stomach or between meals

Neurochem Res 47:517530 Matsuda Y, Ozawa N, Shinozaki T, Wakabayashi KI, Suzuki K, Kawano Y, Ohtsu I, Tatebayashi Y (2020) Ergothioneine, a metabolite of the gut bacterium Lactobacillus reuteri, protects against stress-induced sleep disturbances

[xxv] There is no requirement (including as to timing) as to when this must occur

Clinically manifested as progressive visual field defects and optic nerve damage, the selective and irreversible loss of retinal ganglion cells (RGCs), the central input neurons of the retina, forms the basis of glaucomatous pathology [320]

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This means there will be a period of overlap where both medications are pharmacologically active